2023 NFL Week 10 odds, predictions: Picks, lines, spreads for every game (2024)

National Football League

Updated Nov. 6, 2023 12:55 a.m. ET

The San Francisco 49ers (5-3) play at the Jacksonville Jaguars (6-2) in one of the marquee matchups of NFL Week 10 on Sunday.

The 49ers, coming off a bye, are the co-leaders of the NFC West Division with the Seattle Seahawks.

The Jaguars lead the AFC South.

The game will be at 1 p.m. ET Sunday and can be seen on FOX and the FOX Sports App.

ADVERTIsem*nT

The New York Giants and Dallas Cowboys resume one of the league's most storied rivalries in Texas. The game is at 4:25 p.m. ET on Sunday and can be seen on FOX and the FOX Sports App.

Here's everything you need to know about the NFL odds for Week 10 — the point spread, moneyline and total Over/Under.

All times ET

BYES: Chiefs, Dolphins, Eagles, Rams

THURSDAY'S GAME

Panthers @ Bears (8:15 p.m., Amazon Prime Video)

Point spread:Bears -3 (Bears favored to win by more than 3 points, otherwise Panthers cover)
Moneyline:Bears -160 favorites to win(bet $10 to win $16.25 total);Panthers+135 underdogs to win(bet $10 to win $23.50 total)
Total scoring Over/Under:40.5 points scored by both teams combined

FINAL CAR 13 · CHI 16 NFL SPREADTO WINTOTAL Carolina Panthers CAR Chicago Bears CHI

Josh Dobbs reflects on being traded to the Vikings, leading them to a win

SUNDAY'S GAMES

Colts vs. Patriots @ Frankfurt, Germany (9:30 a.m., NFL Network)

Point spread:Colts -1.5 (Colts favored to win by more than 1.5 points, otherwise Patriots cover)
Moneyline:Colts -127 favorites to win(bet $10 to win $17.87 total);Patriots+107 underdogs to win(bet $10 to win $20.70 total)
Total scoring Over/Under:43.5 points scored by both teams combined

FINAL IND 10 · NE 6 NFL SPREADTO WINTOTAL Indianapolis Colts IND New England Patriots NE

Saints @ Vikings (1 p.m., FOX and FOX Sports App)

Point spread:Saints -2.5 (Saints favored to win by more than 2.5 points, otherwise Vikings cover)
Moneyline:Saints -143 favorites to win(bet $10 to win $16.99 total);Vikings+121 underdogs to win(bet $10 to win $22.10 total)
Total scoring Over/Under:40.5 points scored by both teams combined

FINAL NO 19 · MIN 27 NFL SPREADTO WINTOTAL New Orleans Saints NO Minnesota Vikings MIN

49ers @ Jaguars(1 p.m., FOX and FOX Sports App)

Point spread:49ers -2.5 (49ers favored to win by more than 2.5 points, otherwise Jaguars cover)
Moneyline:49ers -149 favorites to win(bet $10 to win $16.71 total);Jaguars+125 underdogs to win(bet $10 to win $22.50 total)
Total scoring Over/Under:44.5 points scored by both teams combined

FINAL SF 34 · JAX 3 NFL SPREADTO WINTOTAL San Francisco 49ers SF Jacksonville Jaguars JAX

Browns @ Ravens (1 p.m., FOX and FOX Sports App)

Point spread:Ravens -5.5 (Ravens favored to win by more than 5.5 points, otherwise Browns cover)
Moneyline:Ravens -236 favorites to win(bet $10 to win $14.24 total);Browns+194 underdogs to win(bet $10 to win $29.40 total)
Total scoring Over/Under:39 points scored by both teams combined

FINAL CLE 33 · BAL 31 NFL SPREADTO WINTOTAL Cleveland Browns CLE Baltimore Ravens BAL

Texans @ Bengals (1 p.m., CBS)

Point spread:Bengals -8 (Bengals favored to win by more than 8 points, otherwise Texans cover)
Moneyline:Bengals -413 favorites to win(bet $10 to win $12.42 total);Texans+320 underdogs to win(bet $10 to win $42 total)
Total scoring Over/Under:46.5 points scored by both teams combined

FINAL HOU 30 · CIN 27 NFL SPREADTO WINTOTAL Houston Texans HOU Cincinnati Bengals CIN

Packers @ Steelers (1 p.m., CBS)

Point spread:Steelers -3 (Steelers favored to win by more than 3 points, otherwise Packers cover)
Moneyline:Steelers -164 favorites to win(bet $10 to win $16.10 total);Packers+138 underdogs to win(bet $10 to win $23.80 total)
Total scoring Over/Under:37 points scored by both teams combined

FINAL GB 19 · PIT 23 NFL SPREADTO WINTOTAL Green Bay Packers GB Pittsburgh Steelers PIT

Titans @ Buccaneers (1 p.m., CBS)

Point spread:Buccaneers -1 (Buccaneers favored to win by more than 1 point, otherwise Titans cover)
Moneyline:Buccaneers -117 favorites to win(bet $10 to win $18.55 total);Titans-103 underdogs to win(bet $10 to win $19.71 total)
Total scoring Over/Under:39 points scored by both teams combined

FINAL TEN 6 · TB 20 NFL SPREADTO WINTOTAL Tennessee Titans TEN Tampa Bay Buccaneers TB

Falcons @ Cardinals (4:05 p.m., CBS)

Point spread:Falcons -2.5 (Falcons favored to win by more than 2.5 points, otherwise Cardinals cover)
Moneyline:Falcons -130 favorites to win(bet $10 to win $17.69 total);Cardinals+109 underdogs to win(bet $10 to win $20.90 total)
Total scoring Over/Under:41.5 points scored by both teams combined

FINAL ATL 23 · ARI 25 NFL SPREADTO WINTOTAL Atlanta Falcons ATL Arizona Cardinals ARI

Lions @ Chargers (4:05 p.m., CBS)

Point spread:Lions -1.5 (Lions favored to win by more than 1.5 points, otherwise Chargers cover)
Moneyline:Lions -120 favorites to win(bet $10 to win $18.33 total);Chargers+101 underdogs to win(bet $10 to win $20.10 total)
Total scoring Over/Under:48.5 points scored by both teams combined

FINAL DET 41 · LAC 38 NFL SPREADTO WINTOTAL Detroit Lions DET Los Angeles Chargers LAC

Giants @ Cowboys (4:25 p.m., FOX and FOX Sports App)

Point spread:Cowboys -15.5 (Cowboys favored to win by more than 15.5 points, otherwise Giants cover)
Moneyline:Cowboys -1039 favorites to win(bet $10 to win $10.96 total);Giants+660 underdogs to win(bet $10 to win $76 total)
Total scoring Over/Under:39.5 points scored by both teams combined

FINAL NYG 17 · DAL 49 NFL SPREADTO WINTOTAL New York Giants NYG Dallas Cowboys DAL

Commanders @ Seahawks (4:25 p.m., FOX and FOX Sports App)

Point spread:Seahawks -6 (Seahawks favored to win by more than 6 points, otherwise Commanders cover)
Moneyline:Seahawks -261 favorites to win(bet $10 to win $13.83 total);Commanders+209 underdogs to win(bet $10 to win $30.90 total)
Total scoring Over/Under:44.5 points scored by both teams combined

FINAL WAS 26 · SEA 29 NFL SPREADTO WINTOTAL Washington Commanders WAS Seattle Seahawks SEA

Jets @ Raiders (8:20 p.m., NBC)

Point spread:Jets -2 (Jets favored to win by more than 2 points, otherwise Raiders cover)
Moneyline:Jets -126 favorites to win(bet $10 to win $17.81 total);Raiders+107 underdogs to win(bet $10 to win $20.70 total)
Total scoring Over/Under:36.5 points scored by both teams combined

FINAL NYJ 12 · LV 16 NFL SPREADTO WINTOTAL New York Jets NYJ Las Vegas Raiders LV

MONDAY'S GAME

Broncos @ Bills (8:15 p.m. ET, ESPN/ABC)

Point spread:Bills -7.5 (Bills favored to win by more than 7.5 points, otherwise Broncos cover)
Moneyline:Bills -374 favorites to win(bet $10 to win $12.67 total);Broncos+297 underdogs to win(bet $10 to win $39.70 total)
Total scoring Over/Under:45.5 points scored by both teams combined

FINAL DEN 24 · BUF 22 NFL SPREADTO WINTOTAL Denver Broncos DEN Buffalo Bills BUF

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2023 NFL Week 10 odds, predictions: Picks, lines, spreads for every game (39)

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National Football League

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NFL - New Orleans Saints vs. Minnesota Vikings - 11/12/2023
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NFL - New York Giants vs. Dallas Cowboys - 11/12/2023
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2023 NFL Week 10 odds, predictions: Picks, lines, spreads for every game (2024)
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